Kampala, Uganda – April 26, 2025 — Uganda has officially declared an end to the Ebola disease outbreak, less than three months after the virus was first confirmed in the capital, Kampala. The announcement follows 42 days with no new cases, in line with World Health Organization (WHO) guidelines.
The outbreak, confirmed on January 30, 2025, resulted in 14 reported cases — 12 confirmed through laboratory testing and two probable cases. Of these, four people sadly lost their lives, while ten successfully recovered. Health officials closely monitored 534 individuals who had been in contact with confirmed and probable cases.
The country’s rapid response was credited to its long-standing experience in managing infectious diseases. Working closely with WHO and other partners, Uganda’s Ministry of Health quickly activated national coordination systems, deployed rapid response teams, reinforced surveillance, and established treatment units. Measures to prevent cross-border transmission were also intensified, particularly at major points of entry.
“This outbreak challenged us in new ways. It touched both urban and rural communities and unfolded amidst significant global funding constraints,” said Dr. Chikwe Ihekweazu, Acting WHO Regional Director for Africa. “The response demonstrated Uganda’s long-standing leadership in tackling public health emergencies. WHO is extremely proud to have supported these efforts.”
The outbreak involved the Sudan virus disease (SVD) strain, a severe and often fatal type of Ebola. In past outbreaks, SVD has claimed the lives of approximately 40% of those infected. Despite no licensed vaccine for this strain, Uganda launched a rapid clinical trial within days of the outbreak's confirmation, using the ring vaccination approach. Treatment efforts also included the use of Remdesivir under emergency protocols.
WHO mobilized over 130 national and international experts to support Uganda’s response, aiding in case investigations, contact tracing, laboratory testing, and clinical care. More than 1,500 samples were tested, with WHO providing logistics, training, and quality assurance to ensure biosafety standards.
“Uganda’s leadership and resilience were crucial in containing this outbreak,” said Dr. Kasonde Mwinga, WHO Representative in Uganda. “From the very first day, WHO worked hand-in-hand with the Ministry of Health, and the people of Uganda showed extraordinary resolve.”
Although the outbreak has been declared over, Ugandan health authorities, with continued support from WHO and partners, will maintain investments in surveillance, survivor support, and preparedness to guard against future threats.
Uganda’s success story underscores the importance of coordinated efforts, community engagement, and strong health systems in responding to public health emergencies.
